Our new Distinct+ tissue clearing procedure is the only approach that delipidates samples without any alter in morphology and with nominal effect on structural integrity.
Megatome can be a vibrating microtome built to portion a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows significant-throughput tissue sectioning with uniform area profile, as well as minimum tissue injury and data reduction.
Ask for a estimate or demo Uniformly part massive tissues & sample arrays Megatome is the one microtome which will portion samples as significant as intact nonhuman primate and human organs, rendering it a must have for fields for instance neuropathology.
Megatome is designed for accuracy: the blade vibrates at an increased frequency and bigger amplitude selection than other microtomes, and incorporates a unique deflection Handle mechanism.
SE works by using a rotational electrical discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) all through a porous sample without harming electrically charged buildings throughout the tissue. This allows 2-4 day clearing of intact organs,
Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them thoroughly clear. This permits light penetration into your sample and makes certain the acquisition of large-resolution, in-concentrate graphic knowledge.
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eFLASH is actually a rapid tissue labeling procedure that allows for uniform total-organ staining in twenty rounds of labeling.
The SmartSPIM mild sheet microscope provides unparalleled resolution megatomi.com and acquisition pace throughout intact tissue volumes, even though its modular design means that you can improve and customise person parts.
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SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, defending specimens for many rounds of processing.
Leverage the Very clear+ tissue clearing system, coupled with eFLASH and patented stochastic electrotransport technologies, to quickly distinct and label whole organs. Essential highlights and functions include:
Our novel Protect tissue preservation strategy varieties intramolecular bonds applying polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.